The effects of Spirulina on anemia and immune function in senior citizens which was published in 2011.
The study concluded that Spirulina daily supplementation, regardless of other dietary intake, may prove beneficial for major variables associated with anemia. How can SP2 help achieve this?
Taking spirulina allowed for a steady increase in average values of MCH in both male and female subjects. MCH (mean corpuscular hemoglobin) refers to the level of hemoglobin found in the blood. Hemoglobin is a protein in the blood that allows red blood cells to deliver oxygen to the cells and tissues in the body. For people who have anemia, this allows them to carry more hemoglobin.
In addition, MCV and MCHC were also steadily increasing in male subjects. MCV and MCHC can be used to diagnose anemia. Females at more advanced ages appears to benefit quickly from Spirulina supplements.
Subjects were eligible if they had an age > 50 years and a diagnosis of anemia during the previous 12 months. Eligible subjects were then invited to undergo a clinical evaluation for further health history assessment.
Enrolled subjects completed an online dietary questionnaire and once included in the study were instructed to take 6 tablets of 500 mg Spirulina per day for a 12-week period. Blood samples were collected at 0, 6 and 12 weeks.
A total of 148 subjects responded. Of these, 53 subjects were eligible and 40 agreed to undergo a clinical evaluation. Thirty subjects (mean age 63 years) completed the entire study, including dietary questionnaires and 12 weeks of Spirulina supplement.
"Spirulina is an multicellular cyanobacterium within the Oscillatoriaceae algae family which is commonly used as a food additive rich in proteins, carotenoids, vitamins and minerals. Spirulina is not a new drug as its story as a nutritional element is quite old, dating back to the Aztecs. Inhibitory effects of Spirulinaon atherosclerosis were reported possibly via the inhibition of leptin secretion and improvement of leptin resistance. Previous studies support the beneficial effects of Spirulina against fatty liver,oxidative stress, hyperglicemia,hypercholesterolemia, and arterial hypertension.We hypothesized that Spirulina may provide a unique source of nutraceuticals that will enhance the homeostatic hematologic and immunological systems."
Prolonged supplementation, at 12 weeks of Spirulina supplementation, appears to provide the highest benefit to those between 60 and 70 years old among female subjects. Conversely, 50–60 years old male subjects appear to benefit from Spirulina supplementation. In fact, at 6 and 12 weeks of Spirulina supplementation the youngest male group (50–60 years old) had the highest incidence of increase in numerous CBC variables. At 6 and 12 weeks of supplementation, over 50% of male subjects at 50–60 years had increased values in all and 5/7 CBC parameters, respectively. Most importantly, during the study period, there were no significant changes in average dietary intake with respect to total energy, total protein, total fat, total carbohydrate, iron, glutathione, folate, vitamin E, zinc, vitamin A, vitamin B1 and vitamin D.